This Week's Top Stories Concerning ADHD Medication Pregnancy
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The choice of whether to stop or continue ADHD medications during pregnancy and breastfeeding is a difficult decision for women suffering from the condition. There aren't many studies on how exposure to ADHD for a long time could affect the pregnant fetus.
A study recently published in Molecular Psychiatry shows that children exposed to ADHD medication during the uterus do not develop neurological developmental disorders such as hearing loss or impaired vision seizures, febrile seizures or IQ impairment. The authors acknowledge that further high-quality research is needed.
Risk/Benefit Analysis
Women who are pregnant and taking ADHD medication must evaluate the benefits of using it against the possible risks to the fetus. Physicians don't have the data to make unambiguous recommendations however they can provide information on the risks and benefits to help pregnant women make informed decisions.
A study published in Molecular Psychiatry found that women who were taking ADHD medications during early pregnancy did not have a significantly higher risk of fetal cardiac malformations or major structural birth defects. The researchers used a large population-based study of case-control to determine the prevalence of major structural birth defects in infants born to mothers who took stimulants during the early stages of pregnancy, and those who did not. Clinical geneticists and pediatric cardiologists reviewed the cases to ensure an accurate case classification and to limit the chance of bias.
The study conducted by the researchers had some limitations. Most important, they were unable to separate the effects of the medication from those of the underlying disorder. This makes it difficult for researchers to establish whether the few associations observed between the groups that were exposed to medication use or if they were confounded by the presence of comorbidities. Additionally the researchers did not study the long-term effects of offspring on their parents.
The study showed that infants whose mothers took ADHD medication during pregnancy had a higher chance of being admitted to the neonatal care unit (NICU), compared to mothers who did not take any medication during pregnancy or quit taking the medication prior to or during pregnancy. The reason for this was central nervous system disorders. The increased risk of admission was not influenced by the stimulant medications used during pregnancy.
Women who were taking stimulant ADHD medications during pregnancy also had a higher likelihood of having to have caesarean sections or the baby was not scoring well on the Apgar scale (less than 7). These increases didn't seem to be influenced by the type of medication that was used during pregnancy.
The research suggests that the small risk associated with the use of ADHD medications during the early stages of pregnancy may be offset by the greater benefits to both the mother and child of continued treatment for the woman's condition. Physicians should speak with their patients about this issue and as much as possible, assist them develop coping strategies that can lessen the impact of her disorder in her daily life and relationships.
Medication Interactions
As more women than ever before are being diagnosed with ADHD and being treated with medication, the dilemma of whether or not to end treatment during pregnancy is a question that more and more doctors have to face. The majority of these decisions are taken in the absence of clear and authoritative evidence regardless, so doctors must weigh what they know from their own experiences, those of other doctors, and what research says on the topic and their best judgment for each individual patient.
The issue of risk to infants is difficult to determine. The research on this subject is based on observation rather than controlled studies and many of the findings are in conflict. In addition, most studies limit their analysis to live births, which can underestimate severe teratogenic effects that result in abortion or termination of the pregnancy. The study discussed in the journal club addresses these limitations by analyzing both data on live and deceased births.
Conclusion A few studies have shown a positive correlation between ADHD medications and certain birth defects However, other studies haven't established a link. The majority of studies show a neutral, or even slightly negative, impact. Therefore, a careful risk/benefit assessment must be conducted in every instance.
For women suffering from ADHD, the decision to discontinue medication is difficult if not impossible. In fact, in a recent article in the Archives of Women's Mental Health psychologist Jennifer Russell notes that stopping ADHD medication during pregnancy can increase depression, feelings of loneliness, and family conflict for those suffering from the disorder. The loss of medication can also affect the ability to safely drive and complete work-related tasks, which are essential aspects of normal life for those with ADHD.
She recommends that women who are unsure about whether to keep or stop taking medication because of their pregnancy consider educating family members, friends and colleagues about the condition, its impact on daily life, and the advantages of staying on the current treatment regimen. It can also help the woman feel supported as she struggles with her decision. It is important to note that some medications are able to pass through the placenta so if a woman decides to stop her adhd medication options medication during pregnancy and breastfeeding, she should be aware that traces of the medication could be passed on to the baby.
Birth Defects and Risk of
As the use and abuse of ADHD medications to treat the symptoms of attention deficit disorder hyperactivity disorder (ADHD) is increasing, so does concern about the possible effects of the drugs on fetuses. Recent research published in the journal Molecular Psychiatry has added to the body of knowledge regarding this issue. Using two massive data sets researchers were able look at more than 4.3 million pregnancies and see whether stimulant medications increased the risk of birth defects. Although the risk overall is low, the researchers found that exposure in the first trimester to ADHD medications was linked to an increased risk of specific heart defects, such as ventriculo-septal defect (VSD).
The researchers of the study found no connection between the use of early medications and other congenital abnormalities, like facial clefting, or club foot. The results are in agreement with previous studies which showed an insignificant, but small increase in cardiac malformations for women who started taking ADHD medication prior to the time of pregnancy. The risk increased in the latter half of pregnancy when a large number of women decided to stop taking their medication.
Women who used ADHD medications in the first trimester of pregnancy were also more likely to experience caesarean section, low Apgar score following delivery, and a baby that required help breathing at birth. However the researchers of the study were not able to eliminate selection bias by restricting the study to women who didn't have other medical issues that could have contributed to these findings.
The researchers hope their research will aid in the clinical decisions of physicians who see pregnant women. They recommend that, while a discussion of the benefits and risks is important but the decision to stop or continue medication should be based on the woman's needs and the severity of her ADHD symptoms.
The authors caution that, even though stopping the medication is an option to look into, it is not recommended due to the high prevalence of depression and other mental problems in women who are expecting or who have recently given birth. Further, research shows that women who stop taking their medication will have a difficult time adjusting to a life without them once the baby is born.
Nursing
The responsibilities of a new mother can be overwhelming. Women suffering from ADHD can face severe challenges when they have to manage their symptoms, attend doctor appointments and prepare for the birth of a child and adjust to new routines. Therefore, many women decide to continue taking their common adhd medications uk medications throughout pregnancy.
The majority of stimulant medicines are absorbed through breast milk in very small quantities, so the risk to breastfeeding infant is minimal. However, the frequency of exposure to medication by the newborn can vary depending on the dosage, frequency it is taken and the time of day it is administered. Additionally, different medications enter the baby's system differently through the gastrointestinal tract as well as breast milk and the impact of this on a newborn is not fully understood.
Some doctors may decide to stop stimulant medications during a woman's pregnancy due to the lack of research. It's a difficult choice for the mother, who must weigh the benefits of her medication against the risks to the foetus. In the meantime, until more information is available, GPs should ask all pregnant patients about their experience with common adhd medications uk and whether they plan or are taking to take medication during the perinatal time.
Numerous studies have demonstrated that women can continue taking their ADHD medication without risk during pregnancy and while breast-feeding. In response, a rising number of patients are opting to continue their medication. They have discovered after consulting with their doctor that the benefits of keeping their current medication outweigh any possible risks.
It is essential for women with ADHD who are considering breastfeeding to seek out a specialist psychiatrist's advice prior to becoming pregnant. They should review their medications with their physician and discuss the advantages and disadvantages of continuing treatment, including non medication treatment for adhd adults-pharmacological management strategies. Psychoeducation is also necessary to help pregnant women suffering from ADHD recognize the signs and the underlying disorder. They should also be informed about treatment options and build the coping mechanisms. This should involve a multidisciplinary approach with the GP as well as obstetricians, psychiatry and obstetricians. Pregnancy counseling should include a discussion of a treatment plan for the mother as well as the child, monitoring of signs of deterioration and, if necessary modifications to the medication regime.
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